Quelques sujets d'études au CCCF

Quelques sujets d'études

Quantification of nanoparticle endocytosis based on double fluorescent pH-sensitive nanoparticles.
Kurtz-Chalot A, Klein JP, Pourchez J, Boudard D, Bin V, Sabido O, Marmuse L, Cottier M, Forest V.
Biomed Microdevices. 2015 Apr;17(2):42.

Absence of bone sialoprotein (BSP) alters profoundly hematopoiesis and upregulates osteopontin.
Granito RN, Bouleftour W, Sabido O, Lescale C, Thomas M, Aubin JE, Goodhardt M, Vico L, Malaval L.
J Cell Physiol. 2015 Jun;230(6):1342-51.

Bone sialoprotein deficiency impairs osteoclastogenesis and mineral resorption in vitro.
Boudiffa M, Wade-Gueye NM, Guignandon A, Vanden-Bossche A, Sabido O, Aubin JE, Jurdic P, Vico L, Lafage-Proust MH, Malaval L.
J Bone Miner Res. 2010 Dec;25(12):2669-79.Bone Miner Res. 2011 Feb;26(2):439.

Evidence for mitochondrial respiratory deficiency in rat rhabdomyosarcoma cells.
Jahnke VE, Sabido O, Defour A, Castells J, Lefai E, Roussel D, Freyssenet D.
PLoS One. 2010 Jan 8;5(1):e8637. 

Cytostatic factor proteins are present in male meiotic cells and beta-nerve growth factor increases mos levels in rat late spermatocytes.
Perrard MH, Chassaing E, Montillet G, Sabido O, Durand P.
PLoS One. 2009 Oct 5;4(10):e7237. 

Control of mitochondrial biogenesis, ROS level, and cytosolic Ca2+ concentration during the cell cycle and the onset of differentiation in L6E9 myoblasts.
Jahnke VE, Sabido O, Freyssenet D.
Am J Physiol Cell Physiol. 2009 May;296(5):C1185-94. doi: 10.1152/ajpcell.00377.2008. Epub 2009 Mar 18.

Could 99mTc-glucarate be used to evaluate tumour necrosis? In vitro and in vivo studies in leukaemic tumour cell line U937.
Perek N, Sabido O, Le Jeune N, Prevot N, Vergnon JM, Clotagatide A, Dubois F.
Eur J Nucl Med Mol Imaging. 2008 Jul;35(7):1290-8. 

Meiotic progression of rat spermatocytes requires mitogen-activated protein kinases of Sertoli cells and close contacts between the germ cells and the Sertoli cells.
Godet M, Sabido O, Gilleron J, Durand P.
Dev Biol. 2008 Mar 1;315(1):173-88. Epub 2008 Jan 29.